MyBioSource.com's SF3B2 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The SF3B2 Antibody (Center) was generated using Cus1, and SF3B2 as the antigen and it reacts with Human.
Description
This gene encodes subunit 2 of the splicing factor 3b
protein complex. Splicing factor 3b, together with splicing factor
3a and a 12S RNA unit, forms the U2 small nuclear
ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a
complex binds pre-mRNA upstream of the intron's branch site in a
sequence-independent manner and may anchor the U2 snRNP to the
pre-mRNA. Splicing factor 3b is also a component of the minor
U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream
of the branch site at the anchoring site. Subunit 2 also interacts
directly with subunit 4 of the splicing factor 3b complex. Subunit
2 is a highly hydrophilic protein with a proline-rich N-terminus
and a glutamate-rich stretch in the C-terminus. [provided by
RefSeq]